Publication Date
5-2024
Date of Final Oral Examination (Defense)
12-14-2023
Type of Culminating Activity
Thesis
Degree Title
Master of Science in Mechanical Engineering
Department Filter
Mechanical and Biomechanical Engineering
Department
Mechanical and Biomedical Engineering
Supervisory Committee Chair
Clare K. Fitzpatrick, Ph.D.
Supervisory Committee Member
Erin M. Mannen, Ph.D.
Supervisory Committee Member
Trevor Lujan, Ph.D.
Supervisory Committee Member
Gunes Uzer, Ph.D.
Abstract
While it is well-established that early detection and initiation of treatment of developmental dysplasia of the hip is crucial to successful clinical outcome, research on mechanics of the hip joint during healthy and pathological hip development in infants has been limited. Quantification of mechanical behavior in both the healthy and dysplastic developing joints may provide insight into the causes of developmental dysplasia of the hip and facilitate innovation in treatment options. In this study, subject-specific three-dimensional finite element models of two pigs were developed: one healthy pig and one pig with induced dysplasia in the right hindlimb. The objectives of this study were: (1) to characterize mechanical behavior in the acetabular articular cartilage during a normal walking cycle by analyzing six metrics: contact pressure, contact area, strain energy density, von Mises stress, principal stress and principal strain; (2) to quantify the effect on joint mechanics of three anatomic abnormalities previously identified as related to developmental dysplasia of the hip: variation in acetabular coverage, morphological changes in the femoral head, and changes in the articular cartilage. All metrics, except contact area, were elevated in the dysplastic joint. Morphological changes in the femoral head were determined to be the most significant factor in elevating contact pressure in the articular cartilage, while the effects of acetabular coverage and changes in the articular cartilage were less significant.
DOI
https://doi.org/10.18122/td.2207.boisestate
Recommended Citation
Yu, Chia-Yu, "Porcine Computational Modeling to Investigate Developmental Dysplasia of the Hip" (2024). Boise State University Theses and Dissertations. 2207.
https://doi.org/10.18122/td.2207.boisestate
