Synthesis and Characterization of ZnO Nanoparticles from Extracts of Allium sativum and Hydrastis canadensis
Additional Funding Sources
The project described was supported by an Institutional Development Award (IDeA) from the National Institute of General Medical Sciences of the National Institutes of Health under Grant No. P20GM103408.
Abstract
Zinc oxide nanoparticles (ZnO NPs) have become one of the most popular metal oxide nanoparticles for their uses in biomedical applications due to their antibacterial properties. ZnO NPs, when capped with natural products from plant extracts with known antibacterial properties, are hypothesized to cause bacterial stasis and have enhanced bactericidal performance. This project focuses on synthesizing and characterizing natural product capped ZnO NPs and determining how the incorporation of natural products alters the physicochemical properties of ZnO. The ZnO NPs were synthesized using zinc nitrate hexahydrate and aqueous extracts from Allium sativum and Hydrastis canadensis, prepared by alkali precipitation from an aqueous solution at 65°C. These NPs were characterized by TGA-MS, FTIR, XRD, UV-Vis spectroscopy, and SEM. The photocatalytic degradation of malachite green dye by capped ZnO NPs was investigated from an aqueous solution under UVA irradiation, to assess how the incorporation of the plant extract modifies ZnO chemical reactivity. A phytochemical test panel was conducted on the plant extracts of Allium sativum and Hydrastis canadensis using standard biochemical protocols. The research was supported by an Institutional Development Award (IDeA) from the National Institute of General Medical Sciences of the National Institutes of Health under grant P20GM103408.
Synthesis and Characterization of ZnO Nanoparticles from Extracts of Allium sativum and Hydrastis canadensis
Zinc oxide nanoparticles (ZnO NPs) have become one of the most popular metal oxide nanoparticles for their uses in biomedical applications due to their antibacterial properties. ZnO NPs, when capped with natural products from plant extracts with known antibacterial properties, are hypothesized to cause bacterial stasis and have enhanced bactericidal performance. This project focuses on synthesizing and characterizing natural product capped ZnO NPs and determining how the incorporation of natural products alters the physicochemical properties of ZnO. The ZnO NPs were synthesized using zinc nitrate hexahydrate and aqueous extracts from Allium sativum and Hydrastis canadensis, prepared by alkali precipitation from an aqueous solution at 65°C. These NPs were characterized by TGA-MS, FTIR, XRD, UV-Vis spectroscopy, and SEM. The photocatalytic degradation of malachite green dye by capped ZnO NPs was investigated from an aqueous solution under UVA irradiation, to assess how the incorporation of the plant extract modifies ZnO chemical reactivity. A phytochemical test panel was conducted on the plant extracts of Allium sativum and Hydrastis canadensis using standard biochemical protocols. The research was supported by an Institutional Development Award (IDeA) from the National Institute of General Medical Sciences of the National Institutes of Health under grant P20GM103408.