Carrier Protein Mediated Cargo Sensing in Quorum Signal Synthases

Authors

Abu Sayeed Chowdhury, Boise State University
Shibani Basu, Boise State UniversityFollow
Eric Baggs, Boise State UniversityFollow
Lisa Warner, Boise State UniversityFollow
Rajesh Nagarajan, Boise State UniversityFollow

Document Type

Article

Publication Date

1-25-2023

Abstract

Acyl-homoserine lactone synthases make specific AHL quorum sensing signals to aid virulence in Gram-negative bacteria. Here, we use solution NMR spectroscopy to demonstrate that the carrier protein–enzyme interface accurately reveals substrate recognition mechanisms in two quorum signal synthases.

Comments

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Publication Information

Fischer, Patrick D.; Chowdhury, Abu Sayeed; Bartholow, Thomas; Basu, Shibani; Baggs, Eric; Cox, Huel S., III; . . . and Arthanari, Haribabu. (2023). "Carrier Protein Mediated Cargo Sensing in Quorum Signal Synthases". Chemical Communications, 59(8), 1014-1017. https://doi.org/10.1039/D2CC03551K