2026 Undergraduate Research Showcase

Examining the Relationship Between Hypermobile Ehlers-Danlos Syndrome and Mental Health Among Adolescents

Document Type

Student Presentation

Presentation Date

4-24-2026

Faculty Sponsor

Dr. Kruti Chaliawala

Abstract

Background: 1 in 500 people have hypermobility Ehlers-Danlos Syndrome. 81% of the people with HyperMobility Ehlers-Danlos syndrome have been diagnosed with a mental health challenge, such as depression and anxiety. Hypermobile Ehlers-Danlos syndrome (hEDS) is a connective tissue disorder that is associated with chronic pain and physical limitations that can impact mental health. The purpose of this review of literature is to demonstrate the impact that hEDS has on adolescent mental health outcomes. Methods: The current review of literature examines the relationship between hEDS and mental health outcomes such as anxiety, depression, and declines in social interactions often observed in adolescents. Results: Findings consistently show that individuals with hEDS experience higher rates of mental health challenges, such as anxiety, depression, and lower social interactions. These mental health challenges are often linked to chronic pain and fatigue caused by hEDS or the delayed diagnosis. Implication for Public Health: Adolescents suffering from hEDS may elevate anxiety and depression while decreasing social interaction. The outcomes are merely not physical symptoms but a combination of mental health challenges and physical pain, added with fatigue. As adolescents are in the developmental phase of growth, hEDS can really hinder their overall health and well-being.

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