Title

An Algorithm for Partial Functional Differential Equations Modeling Tumor Growth

Document Type

Article

Publication Date

3-18-2018

DOI

http://dx.doi.org/10.1016/j.amc.2017.09.028

Abstract

We introduce a parallel algorithm for the numerical simulation of the growth of human tumor cells in time-varying environments and their response to therapy. The behavior of the cell populations is described by a system of delay partial differential equations with time-dependent coefficients. We construct the new algorithm by developing a time-splitting technique in which the entire problem is split into independent tasks assigned to arbitrary numbers of processors chosen in light of available resources. We present the results of a series of numerical experiments, which confirm the efficiency of the algorithm and exhibit a substantial decrease in computational time thus providing an effective means for fast clinical, case-by-case applications of tumor invasion simulations and possible treatment.

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