To fabricate quantum dot arrays with programmable periodicity, functionalized DNA origami nanotubes were developed. Selected DNA staple strands were biotin-labeled to form periodic binding sites for streptavidin-conjugated quantum dots. Successful formation of arrays with periods of 43 and 71 nm demonstrates precise, programmable, large-scale nanoparticle patterning; however, limitations in array periodicity were also observed. Statistical analysis of AFM images revealed evidence for steric hindrance or site bridging that limited the minimum array periodicity.
Bui, Hieu; Onodera, Craig; Kidwell, Carson; Tan, YerPeng; Graugnard, Elton; Kuang, Wan; Lee, Jeunghoon; Knowlton, William B.; Yurke, Bernard; and Hughes, William L.. (2010). "Programmable Periodicity of Quantum Dot Arrays with DNA Origami Nanotubes". Nano Letters, 10(9), 3367-3372. http://dx.doi.org/10.1021/nl101079u