Title

Anticancer Efficacy of Essential Oils Clove and Cinnamon

Document Type

Student Presentation

Presentation Date

4-21-2014

Faculty Sponsor

Greg Hampikian

Abstract

It has been established that several essential oils have antibacterial and antifungal effects, and in recent years many of these compounds have been analyzed for their potential curative effects against cancer in recent years. Past tests have focused on individual components of essential oils, separating out the constituents and testing them against cancer cells both separately and together. The current study aims to determine the constituents of clove (Syzygium aromaticum) and cinnamon extracts (Cinnamomum verum) through gas chromatography and mass spectrometry analyses. Because past research has examined the increased benefits of using entire essential oils rather than just their constituents, this project will focus on finding a reliable method of dissolving these oils at high and low concentrations. In addition, the oils will be tested against a cancer cell line in each category in the NCI-60 panel and their IC50s will be evaluated using cytotoxicity assays. The primary question being addressed is whether these oils can be used to treat cancer without affecting or harming normal cell lines.

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